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The University of Tennessee, Knoxville

Cellular Aspects of Obesity

Paul Dalhaimer, Assistant ProfessorCollege of Engineering - Chemical and Biomolecular Engineering

Obesity is in large part a consequence of an excessive cellular fraction of neutral lipids, which are sequestered in little-understood bodies called lipid droplets. Neutral lipids and thus droplet(s) are most prevalent in adipocytes, which make up the vast majority of adipose tissue. Dalhaimer will speak about the mechanisms by which lipid droplets form across eukaryotic organisms emphasizing a molecular approach. By determining which cellular factors are responsible for the formation of the droplets, the path to drug design for the treatment of obesity, and potentially heart disease, can be paved.​

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