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The University of Tennessee, Knoxville

Stem Cell Research and Therapy at the University of Tennessee

Madhu Dhar, Associate ProfessorCollege of Veterinary Medicine - Department of Large Animal Clinical Sciences

Stem cell therapy and tissue engineering are the new frontiers of regenerative medicine. Stem cell research has the potential to substantially improve equine medical care. Researchers at the UT College of Veterinary Medicine isolate adult stem cells from bone marrow, fat or peripheral blood, characterize them in culture and then provide them to the clinic for therapy. Stem cells grown in a dish with tissue culture techniques must exhibit three criteria: one is their capability of self-renewal, i.e. stem cells undergo multiple cell divisions while maintaining their undifferentiated state; two is the potential to differentiate into fat, bone, and cartilage; and third is that all stem cells should express a certain set of protein markers. The prospective clinical use of stem cells holds enormous promise for improved treatment of a large number of diseases in horses.​

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